BDBM788177 US12473303, Compound H-APPAMP-034

SMILES CCc4cnn5c(NCc2cn1c(C(F)(F)F)cccc1n2)cc(NC[C@H]3CCNC[C@@H]3O)nc45

InChI Key InChIKey=AXTNZYFHNOPPBL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 788177   

LigandChemical structure of BindingDB Monomer ID 788177BDBM788177(US12473303, Compound H-APPAMP-034)
Affinity DataIC50: 152nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Carrick Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 788177BDBM788177(US12473303, Compound H-APPAMP-034)
Affinity DataIC50: 173nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent