BDBM8327 4-(dimethylamino)-N-{5-phenyl-1H-pyrazolo[3,4-c]pyridazin-3-yl}butanamide::pyrazolopyridazine deriv. 9
SMILES CN(C)CCCC(=O)Nc1n[nH]c2nnc(cc12)-c1ccccc1
InChI Key InChIKey=LDHIZDYQCCLGRS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 8327
Affinity DataKi: 1.70E+3nM ΔG°: -7.76kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair