BDBM84797 PF-00215937::PF-00215955

SMILES Brc1ccc(cc1)-c1c[nH]c(n1)-c1cc2ccccc2cn1

InChI Key InChIKey=BEPPBBZVJDTHTH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 84797   

LigandPNGBDBM84797(PF-00215937 | PF-00215955)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed
LigandPNGBDBM84797(PF-00215937 | PF-00215955)
Affinity DataIC50: 1.65E+4nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed
LigandPNGBDBM84797(PF-00215937 | PF-00215955)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed
LigandPNGBDBM84797(PF-00215937 | PF-00215955)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed
LigandPNGBDBM84797(PF-00215937 | PF-00215955)
Affinity DataIC50: 1.25E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMed