BDBM8613 (4-Pyridylmethylene)tetrahydronaphthalene 4a::4-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemethyl]pyridine::4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]pyridine

SMILES C1C\C(=C/c2ccncc2)c2ccccc2C1

InChI Key InChIKey=WCNFIMZYZJWWCJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8613   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 282nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 143nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 650nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 650nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 650nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed