BDBM86597 Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 2

SMILES COC1CN(C)CCN1c1ccc(Nc2ncc3N(C)C(=O)c4ccccc4N(C)c3n2)cc1

InChI Key InChIKey=GGZJAWQPSMZFEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86597   

TargetAurora kinase A(Human)
Harvard Medical School

LigandChemical structure of BindingDB Monomer ID 86597BDBM86597(Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 2)
Affinity DataIC50: 1.21E+3nMAssay Description:In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Harvard Medical School

LigandChemical structure of BindingDB Monomer ID 86597BDBM86597(Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 2)
Affinity DataIC50: 3.44E+3nMAssay Description:In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2012
Entry Details Article
PubMed