BDBM8712 1,4-Benzodiazepine deriv. 1::methyl 2-(4-methyl-7-{methyl[(1-methyl-1H-indol-2-yl)methyl]carbamoyl}-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl)acetate

SMILES COC(=O)CC1Nc2ccc(cc2CN(C)C1=O)C(=O)N(C)Cc1cc2ccccc2n1C

InChI Key InChIKey=SMHQHIYGXNMNCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8712   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Haemophilus influenzae)
Glaxosmithkline

LigandPNGBDBM8712(1,4-Benzodiazepine deriv. 1 | methyl 2-(4-methyl-7...)
Affinity DataIC50:  6.90E+3nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Glaxosmithkline

LigandPNGBDBM8712(1,4-Benzodiazepine deriv. 1 | methyl 2-(4-methyl-7...)
Affinity DataIC50:  1.65E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed