BDBM87275 N-(1-cyanocyclo- propyl)-9-(5- (difluoromethyl)- 1,3,4-thiadiazol-2-yl)- 4-(1-isoxazolidine- 2-carbonyl)piperidin- 4-yl)-9H-pyrimido [4,5-b]indole-7- sulfonamide::US20250388589, Example 139

SMILES N#CC1(NS(=O)(=O)c2ccc3c4c(C5CCN(C(=O)N6CCCO6)CC5)ncnc4n(-c4nnc(C(F)F)s4)c3c2)CC1

InChI Key InChIKey=DJWGGGOMDDZAHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 87275   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Danatlas Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 87275BDBM87275(N-(1-cyanocyclo- propyl)-9-(5- (difluoromethyl)- 1...)
Affinity DataIC50: 0.000100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent