BDBM8821 3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-methyl-1-(3-methylphenyl)urea::N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N-methyl-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 73

SMILES CN(C(=O)Nc1ccc(cc1)-c1c(C)sc2ncnc(N)c12)c1cccc(C)c1

InChI Key InChIKey=IKEYQAUIFBJKDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8821   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8821(N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50: 1.90E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8821(N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed