BDBM88496 US20250388593, Example 91::tert-Butyl 2-(6,8-dioxo-2,7-diazaspiro [4.6]undecan-2-yl) pyridine-4-carboxylate

SMILES CC(C)(C)OC(=O)c1ccnc(N2CCC3(CCCC(=O)NC3=O)C2)c1

InChI Key InChIKey=CKHMICNOAOPMDO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88496   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 88496BDBM88496(tert-Butyl 2-(6,8-dioxo-2,7-diazaspiro [4.6]undeca...)
Affinity DataKd:  7.50E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent