BDBM915 (R,S)-[Iminobis[1-(cyclohexylmethyl)-2-hydroxy-3,1-propanediyl]]bis[carbamic acid], Bis(1,1-dimethylethylester)::Aminodiol deriv. 9b::tert-butyl N-[(2S,3R)-4-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-4-cyclohexyl-2-hydroxybutyl]amino}-1-cyclohexyl-3-hydroxybutan-2-yl]carbamate

SMILES CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H](O)CNC[C@@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C

InChI Key InChIKey=GFTWFKGCSFRFOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 915   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

LigandPNGBDBM915((R,S)-[Iminobis[1-(cyclohexylmethyl)-2-hydroxy-3,1...)
Affinity DataIC50: 800nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2004
Entry Details Article
PubMed