BDBM92804 Bisanilinopyrimidine, 4c::US9249124, 20

SMILES OC(=O)c1ccc(Nc2nc(Cl)c(Cl)c(Nc3ccccc3C(O)=O)n2)cc1

InChI Key InChIKey=CDGKKEPAUJAQHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92804   

TargetAurora kinase A(Human)
Moffitt Cancer Center

LigandChemical structure of BindingDB Monomer ID 92804BDBM92804(Bisanilinopyrimidine, 4c | US9249124, 20)
Affinity DataIC50: 1.49E+3nMAssay Description:In vitro enzyme activity assay using Aurora Kinase A. More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Moffitt Cancer Center

LigandChemical structure of BindingDB Monomer ID 92804BDBM92804(Bisanilinopyrimidine, 4c | US9249124, 20)
Affinity DataIC50: 1.49E+3nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details
US Patent