BDBM93225 Kinase inhibitor, A2

SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F

InChI Key InChIKey=AMMNITAEKXLTKI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 93225   

TargetAurora kinase A(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 1.88E+5nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 2.60E+4nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 1.31E+5nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 2.50E+4nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 2.52E+5nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetHexokinase-4(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 4.00E+3nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 4.70E+4nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
University of Dundee

LigandPNGBDBM93225(Kinase inhibitor, A2)
Affinity DataIC50: 2.40E+4nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed