BDBM95470 US20250388593, Example 223::tert-Butyl 4-(4,7,9-trioxo-3,8-diazaspiro [5.6]dodecan-3-yl) benzoate (Optically Active A, Example Compound 223) and (Optically Active B, Example Compound 224)

SMILES CC(C)(C)OC(=O)c1ccc(N2CC[C@]3(CCCC(=O)NC3=O)CC2=O)cc1

InChI Key InChIKey=ONWGEIMUOXTXBN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 95470   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 95470BDBM95470(tert-Butyl 4-(4,7,9-trioxo-3,8-diazaspiro [5.6]dod...)
Affinity DataKd: <5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent