BDBM96827 N-(5-((4-chlorobenzyl)oxy)-1,3,4-thiadiazol- 2-yl)-6-cyano-4-(2- methoxyphenyl)nicotinamide::US12509454, Compound 92

SMILES N#Cc1cc(-c2ccccc2OC)c(C(=O)Nc2nnc(OCc3ccc(Cl)cc3)s2)cn1

InChI Key InChIKey=VBZMFMGXAQKXAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96827   

TargetDNA polymerase theta [1-899](Human)
Ideaya Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 96827BDBM96827(N-(5-((4-chlorobenzyl)oxy)-1,3,4-thiadiazol- 2-yl)...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent