BDBM97053 1-(4-(4-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)piperazin-1- yl)phenyl)dihydropyrimidine- 2,4(1H,3H)-dione::US20260000676, Compound A82

SMILES O=C1CCN(c2ccc(N3CCN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC4)CC3)cc2)C(=O)N1

InChI Key InChIKey=MYAPPUHZKDMOPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97053   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97053BDBM97053(1-(4-(4-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman...)
Affinity DataIC50: 2.75E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent