BDBM97128 (3R)-3-((5aS)-7-((8-(2-fluoro-4-((3S,4R)- 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3-yl)methyl)- 1-oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260000676, Compound A158

SMILES O=C1CC[C@@H](N2Cc3c(ccc4c3OC[C@@H]3CN(CC5COC6(CCN(c7ccc([C@@H]8c9ccc(O)cc9OC[C@@H]8c8ccccc8)cc7F)CC6)C5)CCN43)C2=O)C(=O)N1

InChI Key InChIKey=SSDFPGXZLUALMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97128   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97128BDBM97128((3R)-3-((5aS)-7-((8-(2-fluoro-4-((3S,4R)- 7-hydrox...)
Affinity DataIC50: 50nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent