BDBM97135 7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-azaspiro[4.5]decan-3- yl)methyl)piperidin-4- yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A165

SMILES O=C1CC[C@@H](Nc2ccc(C3CCN(C[C@@H]4COC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6)CC5)C4)CC3)c(F)c2)C(=O)N1

InChI Key InChIKey=SCTCXOJSOHBDIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97135   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97135BDBM97135(7-hydroxy-3-phenylchroman-4-yl)phenyl)- 1-oxa-8-az...)
Affinity DataIC50: 275nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent