BDBM99320 US8497281, 98::US9120769, 31::US9663470, 31

SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2nccn2c1

InChI Key InChIKey=DBVFOMYYIPYKCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99320   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99320(US8497281, 98 | US9120769, 31 | US9663470, 31)
Affinity DataIC50: 469nMAssay Description:In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99320(US8497281, 98 | US9120769, 31 | US9663470, 31)
Affinity DataIC50: 469nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99320(US8497281, 98 | US9120769, 31 | US9663470, 31)
Affinity DataIC50: 469nMpH: 6.0Assay Description:n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent