BDBM99554 US8501936, 52

SMILES CC(C)S(=O)(=O)c1ccc(cc1)-c1cccn2nc(Nc3ccc(cc3)N3CCN(C)CC3)nc12

InChI Key InChIKey=XSEFAPQYUPBDKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99554   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandPNGBDBM99554(US8501936, 52)
Affinity DataIC50: 2.10nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandPNGBDBM99554(US8501936, 52)
Affinity DataIC50: 42.4nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Cephalon

US Patent
LigandPNGBDBM99554(US8501936, 52)
Affinity DataIC50: 306nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent