BDBM99825 US8501936, 341

SMILES COc1cc(ccc1-c1cccn2nc(Nc3ccc(cc3)C3CCN(CC(=O)N(C)C)CC3)nc12)C(F)F

InChI Key InChIKey=VTZQFUIZPLDNRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99825   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandPNGBDBM99825(US8501936, 341)
Affinity DataIC50: 33.7nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandPNGBDBM99825(US8501936, 341)
Affinity DataIC50: 91.1nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Cephalon

US Patent
LigandPNGBDBM99825(US8501936, 341)
Affinity DataIC50: 3.00E+3nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent