Compile Data Set for Download or QSAR
Report error Found 379 Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1'
LigandPNGBDBM246890((3R,3aR,6R,6aR)-6-(6-Chloro-5-iodo-3-(2-trimethyls...)
Affinity DataEC50:  284nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246895(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  115nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246992(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  302nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246993(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  3.56E+3nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246994(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  60nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246995(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  450nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246996(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  125nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246997(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  255nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246998(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  282nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM246999(({6-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  193nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247000(({4-[5-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  1.20E+3nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247001(({4-[5-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  109nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247002(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  71nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247003({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofuro...)
Affinity DataEC50:  68nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247004(({4-[5-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  344nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247005(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)
Affinity DataEC50:  74nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM247006(US10053471, 17 | ({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hyd...)
Affinity DataEC50:  84nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM237920(US9394285, 1)
Affinity DataEC50:  4.20nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237921(US9394285, 2)
Affinity DataEC50:  64.7nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237922(US9394285, 3)
Affinity DataEC50:  459nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237923(US9394285, 4)
Affinity DataEC50:  71nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237924(US9394285, 5)
Affinity DataEC50:  35.7nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237925(US9394285, 6)
Affinity DataEC50:  17.3nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237926(US9394285, 7)
Affinity DataEC50:  671nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237927(US9394285, 8)
Affinity DataEC50:  220nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237928(US9394285, 9)
Affinity DataEC50:  71.2nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237929(US9394285, 10)
Affinity DataEC50:  69.9nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237930(US9394285, 11)
Affinity DataEC50:  554nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237931(US9394285, 12)
Affinity DataEC50:  42.5nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237932(US9394285, 13)
Affinity DataEC50:  6.90nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237933(US9394285, 14B | US9394285, 14A | US9394285, 14)
Affinity DataEC50:  151nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237933(US9394285, 14B | US9394285, 14A | US9394285, 14)
Affinity DataEC50:  101nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237933(US9394285, 14B | US9394285, 14A | US9394285, 14)
Affinity DataEC50:  118nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237934(US9394285, 15)
Affinity DataEC50:  632nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237935(US9394285, 16)
Affinity DataEC50:  412nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237936(US9394285, 17)
Affinity DataEC50:  126nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237937(US9394285, 18)
Affinity DataEC50:  182nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237938(US9394285, 19)
Affinity DataEC50:  383nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237939(US9394285, 20)
Affinity DataEC50:  53.6nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237940(US9394285, 21)
Affinity DataEC50:  93.5nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237941(US9394285, 22)
Affinity DataEC50:  13.7nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237942(US9394285, 23)
Affinity DataEC50:  16nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237943(US9394285, 24)
Affinity DataEC50:  252nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237944(US9394285, 25)
Affinity DataEC50:  111nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM60975(4,6-difluoro-5-[4-(1-hydroxy-2-methylpropan-2-yl)p...)
Affinity DataEC50:  125nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237946(US9394285, 27)
Affinity DataEC50:  36.9nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237947(US9394285, 28)
Affinity DataEC50:  1.08E+3nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237948(US9394285, 29)
Affinity DataEC50:  383nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237949(US9394285, 30)
Affinity DataEC50:  30nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

LigandPNGBDBM237950(US9394285, 31)
Affinity DataEC50:  130nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

Displayed 1 to 50 (of 379 total ) | Next | Last >>
Jump to: