Report error Found 150 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2'
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of 5HT-induced intracellular Ca...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as inhibition of glutamate-induced intracellu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 31nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 31nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 102nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 115nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 115nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 117nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 117nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
