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Report error Found 170 Enz. Inhib. hit(s) with Target = 'AMP deaminase'
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096172(1-Bromo-4-[2-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5...)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096172(1-Bromo-4-[2-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant AMPD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096166(1-Benzyloxy-4-[2-(8-hydroxy-7,8-dihydro-6H-imidazo...)
Affinity DataKi:  9nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096165(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  15nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096165(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant AMPD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Astrazeneca R&D

LigandPNGBDBM154583(6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 16nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 1(Mouse)
Astrazeneca R&D

LigandPNGBDBM154584(4-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 1(Rat)
Astrazeneca R&D

LigandPNGBDBM154584(4-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096169(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 1(Human)
Astrazeneca R&D

LigandPNGBDBM154584(4-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 24nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 1(Mouse)
Astrazeneca R&D

LigandPNGBDBM154583(6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 24nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 1(Rat)
Astrazeneca R&D

LigandPNGBDBM154583(6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 27nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50087401(2-[4-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity against porcine heart or recombinant human E-type AMPDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096170(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610224(CHEMBL5269095)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 1(Human)
Astrazeneca R&D

LigandPNGBDBM154583(6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 38nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096167(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50087407(2-[4-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against porcine heart or recombinant human E-type AMPDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Mouse)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610231(CHEMBL5271711)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant mouse AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50087409(2-[4-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  41nMAssay Description:Inhibitory activity against porcine heart or recombinant human E-type AMPDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096164(1,3-Dichloro-4-[2-(8-hydroxy-7,8-dihydro-6H-imidaz...)
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610231(CHEMBL5271711)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 1(Rabbit)
Agrevo

Curated by ChEMBL
LigandPNGBDBM50004698(CHEMBL1160282)
Affinity DataIC50: 70nMAssay Description:Inhibition of Oryctolagus cuniculus (rabbit) muscle adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM154583(6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 75nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096171(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  90nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase(Mouse-ear cress)
Agrevo

Curated by ChEMBL
LigandPNGBDBM50004698(CHEMBL1160282)
Affinity DataIC50: 100nMAssay Description:Inhibition of Pisum sativum (pea) adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610244(CHEMBL5272816)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610242(CHEMBL5270167)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Mouse)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610244(CHEMBL5272816)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant mouse AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610243(CHEMBL5287644)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610237(CHEMBL5287535)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610236(CHEMBL5276735)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50087411(2-Benzyl-2-[4-(8-hydroxy-7,8-dihydro-6H-imidazo[4,...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against porcine heart or recombinant human E-type AMPDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610246(CHEMBL5281489)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610228(CHEMBL5284620)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610234(CHEMBL5289502)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610245(CHEMBL5281034)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610233(CHEMBL5271550)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096175(4-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  220nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610226(CHEMBL5266374)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50087408(2-[4-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  250nMAssay Description:Inhibitory activity against porcine heart or recombinant human E-type AMPDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610230(CHEMBL5283087)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610238(CHEMBL5284666)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610223(CHEMBL5280447)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAMP deaminase 2(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50610235(CHEMBL5277889)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human AMPD2 using AMP as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAMP deaminase 2(Human)
Astrazeneca R&D

LigandPNGBDBM50087295(2-(2-Bromo-benzyl)-6-(8-hydroxy-7,8-dihydro-6H-imi...)
Affinity DataKi:  300nMAssay Description:Evaluated for the inhibition of porcine heart or human L-type Adenosine 5'-monophosphate deaminase (AMPDA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096168(1-Benzyloxy-4-[2-(8-hydroxy-7,8-dihydro-6H-imidazo...)
Affinity DataKi:  300nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 2(Rat)
Astrazeneca R&D

LigandPNGBDBM154584(4-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50: 300nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50096162(1,3-Dichloro-4-[2-(8-hydroxy-7,8-dihydro-6H-imidaz...)
Affinity DataKi:  300nMAssay Description:Inhibition of recombinant human E-type adenylate deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAMP deaminase 3(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50087414(2-[4-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]...)
Affinity DataKi:  360nMAssay Description:Inhibitory activity against porcine heart or recombinant human E-type AMPDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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