Compile Data Set for Download or QSAR
Report error Found 764 Enz. Inhib. hit(s) with Target = 'Baculoviral IAP repeat-containing protein 3'
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50255183((1S,3S,6S,10aS)-1-benzyl-6-((S)-2-(methylamino)pro...)
Affinity DataKi:  0.25nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205355(US9249151, 1)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205369(US9249151, 15)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205368(US9249151, 14)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205362(US9249151, 8 | US9249151, 9)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205362(US9249151, 8 | US9249151, 9)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205365(US9249151, 11)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205375(US9249151, 21 | US9249151, 60)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205407(US9249151, 53)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205406(US9249151, 52)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205376(US9249151, 22)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205370(US9249151, 16)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205402(US9249151, 48)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205405(US9249151, 51)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205372(US9249151, 18)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205415(US9249151, 61)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205416(US9249151, 62)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205378(US9249151, 24)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205413(US9249151, 59)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205380(US9249151, 26)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM26223((3S,6S,10aS)-6-[(2S)-2-(methylamino)propanamido]-5...)
Affinity DataKi:  1nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343521((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50393632(CHEMBL2158601)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to BIR3 domain of cIAP2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50425719(CHEMBL2316217)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710516(US20250002493, Embodiment 36 | US20250002493, Comp...)
Affinity DataKi:  1.5nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710524(US20250002493, Embodiment 48 | US20250002493, Comp...)
Affinity DataKi:  1.5nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710529(US20250002493, Embodiment 55 | US20250002493, Comp...)
Affinity DataKi:  1.60nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50393631(CHEMBL2158600)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to BIR3 domain of cIAP2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50393507(CHEMBL2158053)
Affinity DataKi:  1.70nMAssay Description:Competitive inhibition of human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) after 2 to 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50425721(CHEMBL2311586)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710513(US20250002493, Embodiment 25 | US20250002493, Comp...)
Affinity DataKi:  1.70nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710515(US20250002493, Embodiment 34 | US20250002493, Comp...)
Affinity DataKi:  1.80nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM26218((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataKi:  1.84nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM312968(US9605022, Example 3)
Affinity DataIC50: 1.90nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50393508(CHEMBL2158054)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) assessed as dissociation constant after 2 to 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710534(US20250002493, Embodiment 61 | US20250002493, Comp...)
Affinity DataKi:  1.90nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

LigandPNGBDBM312982(US9605022, Example 15)
Affinity DataIC50: 1.90nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50393630(CHEMBL2158599)
Affinity DataKi:  2nMAssay Description:Binding affinity to BIR3 domain of cIAP2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343524((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM312990(US9605022, Example 19)
Affinity DataIC50: 2nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205356(US9249151, 2)
Affinity DataIC50: 2nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205367(US9249151, 13)
Affinity DataIC50: 2nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343522((S,3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343518((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343519((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343523((S,3S,3'S,6S,6'S,1'aS,1'a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cIAP2 BIR3 domain after 2 to 3 hrs by fluorescence polarization-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50343522((S,3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-(1,1'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to BIR3 domain of cIAP2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50255244((1S,3S,6S,10aS,Z)-1-benzyl-6-((S)-2-(methylamino)p...)
Affinity DataKi:  2.09nMAssay Description:Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710531(US20250002493, Embodiment 57 | US20250002493, Comp...)
Affinity DataKi:  2.10nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50425728(CHEMBL2365533)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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