Compile Data Set for Download or QSAR
Report error Found 189 Enz. Inhib. hit(s) with Target = 'Bone morphogenetic protein receptor type-2'
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human BMPR2 using myelin basic protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616958(CHEMBL5404016)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616937(CHEMBL5404269)
Affinity DataKi:  6.20nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616956(CHEMBL5422418)
Affinity DataKi:  7nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616939(CHEMBL5434353)
Affinity DataKi:  8nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  15nMAssay Description:Binding affinity to human BMPR2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50434751(CHEMBL2385579)
Affinity DataIC50: 16nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616951(CHEMBL5420022)
Affinity DataKi:  16nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616954(CHEMBL5437902)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616944(CHEMBL5398151)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616938(CHEMBL5436042)
Affinity DataKi:  22nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50: 24nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 36nMAssay Description:Inhibition of BMPR2 (174 to end residues) (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616941(CHEMBL5428614)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616946(CHEMBL5402879)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  56nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  56nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50: 59nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 74nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 74nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50613307(CHEMBL5271697)
Affinity DataKd:  84nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616947(CHEMBL5421520)
Affinity DataKi:  88nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  89nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616948(CHEMBL5409160)
Affinity DataKi:  118nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataKd:  186nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50507816(Bms-986165 | Deucravacitinib | US12351572, Example...)
Affinity DataIC50: 193nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616959(CHEMBL5438355)
Affinity DataKi: >200nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616960(CHEMBL5417301)
Affinity DataKi: >200nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  200nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  200nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  200nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616952(CHEMBL5408480)
Affinity DataKi:  220nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616953(CHEMBL5397482)
Affinity DataKi:  220nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616957(CHEMBL5399442)
Affinity DataKi:  236nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616945(CHEMBL5400260)
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50602057(CHEMBL1908842 | JNJ-28312141)
Affinity DataKd:  310nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...)
Affinity DataKd:  310nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616950(CHEMBL5438139)
Affinity DataKi:  310nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  370nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50616955(CHEMBL5411422)
Affinity DataKi:  430nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50613308(CHEMBL5271220)
Affinity DataIC50: 461nMAssay Description:Inhibition of BMPR2 (174 to end residues) (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50585191(CHEMBL5079149)
Affinity DataIC50: 488nMAssay Description:Inhibition of 1recombinant human BMPR2 (172 to 734 residues) using myelin basic protein as substrate incubated for 120 mins in presence of [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50613307(CHEMBL5271697)
Affinity DataIC50: 506nMAssay Description:Inhibition of BMPR2 (174 to end residues) (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  570nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  570nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  570nMAssay Description:Binding affinity to BMPR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  570nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  570nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  580nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50613309(CHEMBL5278418)
Affinity DataIC50: 630nMAssay Description:Inhibition of BMPR2 (174 to end residues) (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
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