Compile Data Set for Download or QSAR
Report error Found 390 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]'
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205431BDBM205431((6S+2S)-PEG1 (7))
Affinity DataKd:  0.0100nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205432BDBM205432((6S+2S)-PEG2 (8))
Affinity DataKd:  0.0140nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205434BDBM205434((6S+2S)-PEG4 (10))
Affinity DataKd:  0.0230nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205435BDBM205435((6S+2S)-PEG7 (11))
Affinity DataKd:  0.0260nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205433BDBM205433((6S+2S)-PEG3 (9))
Affinity DataKd:  0.0290nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205430BDBM205430((6S+2S)-PEG0 (6))
Affinity DataKd:  0.0340nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205438BDBM205438(6S+IBET-PEG2 (19))
Affinity DataKd:  0.0620nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205453BDBM205453(MTI (35))
Affinity DataKi:  0.0990nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205431BDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.180nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 50260101BDBM50260101(CHEMBL4068487 | US10689390, Compound 38 | US113193...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684552BDBM684552(US12030880, Example 18)
Affinity DataIC50: 0.640nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205431BDBM205431((6S+2S)-PEG1 (7))
Affinity DataIC50: 0.758nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205435BDBM205435((6S+2S)-PEG7 (11))
Affinity DataIC50: 0.789nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684529BDBM684529(US12030880, Example 4)
Affinity DataIC50: 0.930nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 448073BDBM448073(US10689390, Compound 23 | US11319326, Compound 23)
Affinity DataIC50: 1nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 209487BDBM209487(US9266891, III-28 | US10328074, Example III-28 | U...)
Affinity DataIC50: 1nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 209487BDBM209487(US9266891, III-28 | US10328074, Example III-28 | U...)
Affinity DataIC50: 1nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205456BDBM205456((2S+2S)-PEG1 (5))
Affinity DataIC50: 1.17nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205432BDBM205432((6S+2S)-PEG2 (8))
Affinity DataIC50: 1.28nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684521BDBM684521(US12030880, Example 2)
Affinity DataIC50: 1.40nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 448074BDBM448074(US10689390, Compound 25 | US11319326, Compound 25)
Affinity DataIC50: 1.60nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 50260078BDBM50260078(CHEMBL4095826 | US10689390, Compound 26 | US113193...)
Affinity DataIC50: 2nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205433BDBM205433((6S+2S)-PEG3 (9))
Affinity DataIC50: 2.25nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684543BDBM684543(US12030880, Example 8)
Affinity DataIC50: 2.40nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205434BDBM205434((6S+2S)-PEG4 (10))
Affinity DataIC50: 2.95nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 242688BDBM242688(US9422290, I-1)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 209474BDBM209474(US9266891, III-15 | US10328074, Example III-15 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 209474BDBM209474(US9266891, III-15 | US10328074, Example III-15 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 242713BDBM242713(US9422290, III-2)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 50260080BDBM50260080(CHEMBL4088097 | US10689390, Compound 14 | US113193...)
Affinity DataIC50: 3nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 242714BDBM242714(US9422290, III-3)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 209481BDBM209481(US9266891, III-22 | US10328074, Example III-22 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 242696BDBM242696(US9422290, II-3)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 209482BDBM209482(US9266891, III-23 | US10328074, Example III-23 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 209482BDBM209482(US9266891, III-23 | US10328074, Example III-23 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 209481BDBM209481(US9266891, III-22 | US10328074, Example III-22 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684544BDBM684544(US12030880, Example 9)
Affinity DataIC50: 3nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 242702BDBM242702(US9422290, II-9)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205453BDBM205453(MTI (35))
Affinity DataKd:  3.09nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205430BDBM205430((6S+2S)-PEG0 (6))
Affinity DataIC50: 3.58nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 209457BDBM209457(US9266891, II-1 | US10328074, Example II-1 | US110...)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 448081BDBM448081(US10689390, Compound 37 | US11319326, Compound 37)
Affinity DataIC50: 4nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 209508BDBM209508(US9266891, III-49 | US10328074, Example III-49 | U...)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 448083BDBM448083(US10689390, Compound 39 | US11319326, Compound 39)
Affinity DataIC50: 4nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 209457BDBM209457(US9266891, II-1 | US10328074, Example II-1 | US110...)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 209508BDBM209508(US9266891, III-49 | US10328074, Example III-49 | U...)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 242701BDBM242701(US9422290, II-8)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684547BDBM684547(US12030880, Example 12)
Affinity DataIC50: 4.10nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 448076BDBM448076(US10689390, Compound 27 | US11319326, Compound 27)
Affinity DataIC50: 4.40nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 684549BDBM684549(US12030880, Example 15)
Affinity DataIC50: 4.5nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

Displayed 1 to 50 (of 390 total ) | Next | Last >>
Jump to: