Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2 [A65S,N67Q,E69T,I91L,F131V,K170E,L204A]'
LigandPNGBDBM210938(4-(3-quinolinyl)-benzenesulfonamide (4p))
Affinity DataKi:  0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2017
Entry Details Article
PubMed
LigandPNGBDBM210935(4-(phenyl)-bezenesulfonamide (4a))
Affinity DataKi:  0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2017
Entry Details Article
PubMed
LigandPNGBDBM210936(4-(2-methylphenyl)-bezenesulfonamide (4b))
Affinity DataKi:  20nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2017
Entry Details Article
PubMed
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM210937(4-(3-formylphenyl)-benzenesulfonamide (4e))
Affinity DataKi:  99nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2017
Entry Details Article
PubMed