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Report error Found 179 Enz. Inhib. hit(s) with Target = 'Casein kinase I isoform gamma-2'
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CK1g2 using KRRRAL[pS]VASLPGL as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400754(CHEMBL2203564)
Affinity DataIC50: 3nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400756(CHEMBL2203562)
Affinity DataIC50: 3nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400753(CHEMBL2203565)
Affinity DataIC50: 4nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400755(CHEMBL2203563)
Affinity DataIC50: 5nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400757(CHEMBL2203561)
Affinity DataIC50: 5nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400748(CHEMBL2203556)
Affinity DataIC50: 8nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400752(CHEMBL2203552)
Affinity DataIC50: 8nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400750(CHEMBL2203554)
Affinity DataIC50: 17nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400745(CHEMBL2203559)
Affinity DataIC50: 24nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400744(CHEMBL2203560)
Affinity DataIC50: 26nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400749(CHEMBL2203555)
Affinity DataIC50: 33nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400753(CHEMBL2203565)
Affinity DataIC50: 44nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400751(CHEMBL2203553)
Affinity DataIC50: 50nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400747(CHEMBL2203557)
Affinity DataIC50: 80nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400753(CHEMBL2203565)
Affinity DataIC50: 87nMAssay Description:Inhibition of human CK1-gamma2 in HEK293 cells assessed as inhibition of doxcycline-induced LRP6 phosphorylation after 2 hrs by electrochemiluminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  87nMAssay Description:Binding affinity to human CSNK1G2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to CSNK1G2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  110nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  110nMAssay Description:Binding constant for full-length CSNK1G2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  110nMAssay Description:Binding affinity to CSNK1G2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  110nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400755(CHEMBL2203563)
Affinity DataIC50: 200nMAssay Description:Inhibition of human CK1-gamma2 in HEK293 cells assessed as inhibition of doxcycline-induced LRP6 phosphorylation after 2 hrs by electrochemiluminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400755(CHEMBL2203563)
Affinity DataIC50: 254nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  270nMAssay Description:Binding affinity to CSNK1G2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400752(CHEMBL2203552)
Affinity DataIC50: 348nMAssay Description:Inhibition of human CK1-gamma2 in HEK293 cells assessed as inhibition of doxcycline-induced LRP6 phosphorylation after 2 hrs by electrochemiluminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  380nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400756(CHEMBL2203562)
Affinity DataIC50: 394nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400754(CHEMBL2203564)
Affinity DataIC50: 537nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  580nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400757(CHEMBL2203561)
Affinity DataIC50: 584nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50390500(CHEMBL2071614)
Affinity DataIC50: 700nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  740nMAssay Description:Binding constant for full-length CSNK1G2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  740nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  780nMAssay Description:Binding constant for full-length CSNK1G2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  780nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  780nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  790nMAssay Description:Binding constant for full-length CSNK1G2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  790nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  790nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400744(CHEMBL2203560)
Affinity DataIC50: 840nMAssay Description:Inhibition of human CK1-gamma2 in HEK293 cells assessed as inhibition of doxcycline-induced LRP6 phosphorylation after 2 hrs by electrochemiluminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400746(CHEMBL2203558)
Affinity DataIC50: 853nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  950nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  950nMAssay Description:Binding constant for full-length CSNK1G2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  950nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSNK1G2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSNK1G2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM50400744(CHEMBL2203560)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of human CK1gamma2 using KRRRAL[pS]VASLPGL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
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