Compile Data Set for Download or QSAR
Report error Found 3469 Enz. Inhib. hit(s) with Target = 'DCN1-like protein 1'
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525311(CHEMBL4448070)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584177(CHEMBL5076401)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM768567(US12409171, REGNO SJ000398145)
Affinity DataIC50: 2.77nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM518898(US11116757, No. A193)
Affinity DataIC50: 2.90nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584172(CHEMBL5075399)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM519032(US11116757, No. B19)
Affinity DataIC50: 4nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50271360(CHEMBL4128590 | US12012467, Compound DI-70)
Affinity DataKd:  4.10nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
LigandPNGBDBM50079170(1-(1-Benzyl-piperidin-4-yl)-3-phenyl-urea | CHEMBL...)
Affinity DataIC50: 4.10nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM519034(US11116757, No. B21)
Affinity DataIC50: 4.10nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandPNGBDBM518647(US11116757, No. A1)
Affinity DataIC50: 4.30nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584163(CHEMBL5070367)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584157(CHEMBL5091659)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM768567(US12409171, REGNO SJ000398145)
Affinity DataIC50: 5.64nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50271364(CHEMBL4129669 | US12012467, Compound DI-431)
Affinity DataKd:  5.70nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584169(CHEMBL5092564)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50271361(CHEMBL4127438 | US12012467, Compound DI-404)
Affinity DataKd:  6.70nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
LigandPNGBDBM518656(US11116757, No. A2)
Affinity DataIC50: 6.80nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50271312(CHEMBL4129556 | US12012467, Compound DI-64)
Affinity DataKd:  8.10nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataKi:  8.30nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50271359(CHEMBL4128753 | US12012467, Compound DI-71)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
LigandPNGBDBM768568(US12409171, REGNO SJ000400727)
Affinity DataIC50: 8.51nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM681149(US12012467, Example 3 | US12012467, Compound DI-83...)
Affinity DataIC50: 9.20nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584179(CHEMBL5086499)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50621125(CHEMBL5315233)
Affinity DataIC50: 11nMAssay Description:Inhibition of DCN1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584170(CHEMBL5082310)
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50621125(CHEMBL5315233)
Affinity DataIC50: 11nMAssay Description:Inhibition of DCN1 (unknown origin) by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584160(CHEMBL5078162)
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525354(CHEMBL4517307 | US12012467, Compound DI-591)
Affinity DataKi:  12nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibition of constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584173(CHEMBL5089618)
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525354(CHEMBL4517307 | US12012467, Compound DI-591)
Affinity DataKi:  12nMAssay Description:Inhibition of DCN1 (unknown origin) assessed as inhibition constant incubated for 30 min by competitive FP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584178(CHEMBL5091608)
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584176(CHEMBL5085047)
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  14nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  14nMAssay Description:Binding affinity to N-terminal GST tagged recombinant human DCN1 (58 to 259 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM768569(US12409171, REGNO SJ000401413)
Affinity DataIC50: 14.2nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642832(CHEMBL5591297)
Affinity DataIC50: 15nMAssay Description:Inhibition of DCN1 (unknown origin) by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataIC50: 16nMAssay Description:Binding affinity to N-terminal GST tagged recombinant human DCN1 (58 to 259 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584188(CHEMBL5074683)
Affinity DataIC50: 17nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50271364(CHEMBL4129669 | US12012467, Compound DI-431)
Affinity DataIC50: 17.9nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

LigandPNGBDBM518671(US11116757, No. A3)
Affinity DataIC50: 18nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50245154(CHEMBL4067795 | US11116757, No. A10)
Affinity DataIC50: 18nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584184(CHEMBL5089246)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  21nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human DCN1 expressed in Escherichia coli BL21-AI assessed as reduction in DCN1-FAM-labelled N-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584183(CHEMBL5089944)
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569321(CHEMBL4851208)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human His-tagged DCN1 (58 to 259 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in DCN1/UBC12 int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525354(CHEMBL4517307 | US12012467, Compound DI-591)
Affinity DataIC50: 21nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant human DCN1 expressed in Escherichia coli BL21-AI assessed as reduction in DCN1-FAM-labelled N-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM681106(US12012467, Example 127 | US12012467, Compound DI-...)
Affinity DataIC50: 21.9nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569336(CHEMBL4865016)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant human His-tagged DCN1 (58 to 259 residues) expressed in Escherichia coli BL21 (DE3) using MIKLFSLKQQKKEEESAGGTK-biotin as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
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