Report error Found 4303 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Human)
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.0600nM ΔG°: -57.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0660nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Human)
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.140nM ΔG°: -55.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Human)
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.180nM ΔG°: -55.1kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair











































