Compile Data Set for Download or QSAR
Report error Found 1154 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK2'
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  1.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  1.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  1.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  1.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31099(CHEMBL45741 | Flavopiridol | cid_24867231 | 2-(2-c...)
Affinity DataKd:  2.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  290nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  420nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  3.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  860nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataKd:  700nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  150nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  8.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  318nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CLK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  396nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged CLK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50567047(CHEMBL4848254)
Affinity DataKd:  220nMAssay Description:Binding affinity to wild-type human partial length CLK2 (D144 to R498 residues) expressed in bacterial expression system measured after 1 hr by compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM8274(3-(2-chlorophenyl)-4-{[4-(methylsulfanyl)phenyl]am...)
Affinity DataKd:  460nMAssay Description:Inhibition of wild-type human partial length CLK2 (D144 to R498 residues) expressed in bacterial expression system by Kinomescan method relative to c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50581211(CHEMBL5093650)
Affinity DataKd:  0.900nMAssay Description:Inhibition of human partial length CLK2 (D144/R498) expressed in bacterial system by DiscoveryX Kinomescan binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataKd:  19nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  0.0960nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  0.0960nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  12nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50024294(SP-600125)
Affinity DataKd:  300nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd:  1.90E+3nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  190nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataKd:  470nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  1.40E+3nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  700nMAssay Description:Average Binding Constant for CLK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50632896(CHEMBL5434183)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50632897(CHEMBL5425043)
Affinity DataKd:  82nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50632898(CHEMBL5416758)
Affinity DataKd:  64nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50632905(CHEMBL5414359)
Affinity DataKd:  36nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50632918(CHEMBL5396725)
Affinity DataKd:  68nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd:  18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  4.33E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  7.56E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50273635(1-(4-methyl-2,5-di(pyridin-4-yl)-1H-pyrrol-3-yl)et...)
Affinity DataKd:  10nMAssay Description:Binding affinity to human CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM80396(cid_1893667 | (1E)-1-(3-ethyl-5-methoxy-1,3-benzot...)
Affinity DataKd:  95nMAssay Description:Binding affinity to Clk2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  680nMAssay Description:Binding affinity to Clk2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  860nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  44nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  20nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50342892(6-(benzo[d][1,3]dioxol-5-yl)-N-((tetrahydrofuran-3...)
Affinity DataKd:  320nMAssay Description:Binding affinity to human Clk2 More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50342910(6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylthiazol-4...)
Affinity DataKd:  380nMAssay Description:Binding affinity to human Clk2 More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50342916(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((2-methyl...)
Affinity DataKd:  59nMAssay Description:Binding affinity to human Clk2 More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
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