Compile Data Set for Download or QSAR
Report error Found 330 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-18,20-1210,C797S]'
TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717429BDBM717429(3-{3-(4-fluorophenyl)-4-[6-(1- methyl-1H-pyrazol-4...)
Affinity DataIC50: 0.0500nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717350BDBM717350(3-[3-(4-fluorophenyl)-4-(8- phenyl-9H-purin-6-yl)-...)
Affinity DataIC50: 0.0600nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717395BDBM717395(3-{3-(4-fluorophenyl)-4-[6-(1H- imidazol-4-yl)furo...)
Affinity DataIC50: 0.0600nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717425BDBM717425((1S,3S)-3-[3-(4-fluorophenyl)-4- (6-phenylfuro[2,3...)
Affinity DataIC50: 0.0600nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717455BDBM717455(1-{3-(4-fluorophenyl)-4-[6-(5- methoxypyridin-2-yl...)
Affinity DataIC50: 0.0700nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717208BDBM717208(3-[4-(4-fluorophenyl)-5-{2-[4- (4-methylpiperazin-...)
Affinity DataIC50: 0.0770nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717444BDBM717444(3-{3-(4-fluorophenyl)-4-[6-(1- methyl-1H-imidazol-...)
Affinity DataIC50: 0.0780nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717448BDBM717448(3-{3-(4-fluorophenyl)-4-[6- (pyridin-2-yl)furo[2,3...)
Affinity DataIC50: 0.0820nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717426BDBM717426((1R,3R)-3-[3-(4-fluorophenyl)-4- (6-phenylfuro[2,3...)
Affinity DataIC50: 0.0900nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717306BDBM717306(3-[3-(4-fluorophenyl)-4-(8- phenyl-9H-purin-6-y1)-...)
Affinity DataIC50: 0.0900nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717431BDBM717431(1-{3-(4-fluorophenyl)-4-[6- (1,3,5-trimethyl-1H-py...)
Affinity DataIC50: 0.0900nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717197BDBM717197(3-[4-(4-fluorophenyl)-5-{2-[4- (4-methylpiperazin-...)
Affinity DataIC50: 0.0930nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717445BDBM717445(2,2-difluoro-3-{3-(4- fluorophenyl)-4-[6-(1-methyl...)
Affinity DataIC50: 0.0940nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717438BDBM717438(4-{3-(4-fluorophenyl)-1-[(1s,3s)- 3-(methanesulfon...)
Affinity DataIC50: 0.100nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717447BDBM717447(3-{3-(4-fluorophenyl)-4-[6- (pyridin-3-y1)furo[2,3...)
Affinity DataIC50: 0.104nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717458BDBM717458((1r,3r)-3-{4-[6-(1,3-dimethyl- 1H-pyrazol-4-yl)fur...)
Affinity DataIC50: 0.106nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717273BDBM717273(2-[3-(4-fluorophenyl)-4-(6- phenylfuro[2,3-d]pyrim...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717433BDBM717433(1-{3-(4-fluorophenyl)-4-[6-(1- methyl-1H-imidazol-...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717352BDBM717352(3-{3-(4-fluorophenyl)-4-[6- (pyridin-2-yl)furo[2,3...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717384BDBM717384(3-[3-(4-fluorophenyl)-4-(6-{3- [(4-methylpiperazin...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717462BDBM717462(3-{4-[3-(4-fluorophenyl)-1-(2- hydroxy-2-methylpro...)
Affinity DataIC50: 0.113nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717189BDBM717189(3-[3-(4-fluorophenyl)-4-{2-[4- (4-methylpiperazin-...)
Affinity DataIC50: 0.113nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717212BDBM717212(3-[3-(4-fluorophenyl)-4-{6-[4- (4-methylpiperazin-...)
Affinity DataIC50: 0.119nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717299BDBM717299((1s,3s)-3-(3-(4-fluorophenyl)-4- (6-phenylfuro[2,3...)
Affinity DataIC50: 0.120nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717309BDBM717309(1-[3-(4-fluorophenyl)-4-(8- phenyl-9H-purin-6-yl)-...)
Affinity DataIC50: 0.120nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717188BDBM717188(3-[3-(4-fluorophenyl)-4-(6- phenyl-7H-pyrrolo[2,3-...)
Affinity DataIC50: 0.121nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717457BDBM717457((1r,3r)-3-{3-(4-fluorophenyl)-4- [6-(1-methyl-1H-i...)
Affinity DataIC50: 0.123nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717379BDBM717379(3-{3-(4-fluorophenyl)-4-[6-(1- methyl-1H-imidazol-...)
Affinity DataIC50: 0.130nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717282BDBM717282(N-{2-[3-(4-fluorophenyl)-4-(6- phenylfuro[2,3-d]py...)
Affinity DataIC50: 0.130nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717443BDBM717443(4-{1-[(1s,3s)-3- fluorocyclobutyl]-3-(4- fluorophe...)
Affinity DataIC50: 0.135nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717382BDBM717382(N-(3-{4-[1-(1,1-dioxo-126- thietan-3-yl)-3-(4-fluo...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717300BDBM717300((1r,3r)-3-(3-(4-fluorophenyl)-4- (6-phenylfuro[2,3...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717362BDBM717362(2-{4-[1-(1,1-dioxo-1lambda6-thietan- 3-yl)-3-(4-fl...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717403BDBM717403(3-{3-(4-fluorophenyl)-4-[6-(2- methyl-1,3-thiazol-...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717340BDBM717340(3-[3-(4-fluorophenyl)-4-(6- phenylfuro[2,3-d]pyrim...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717186BDBM717186(3-[3-(4-fluorophenyl)-4-(8- phenyl-9H-purin-6-yl)-...)
Affinity DataIC50: 0.148nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717442BDBM717442(4-[1-(3,3-difluoropropyl)-3-(4- fluorophenyl)-1H-p...)
Affinity DataIC50: 0.153nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717437BDBM717437(1-{4-[6-(1,5-dimethyl-1H- pyrazol-4-yl)furo[2,3- d...)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717415BDBM717415(3-{3-(4-fluorophenyl)-4-[6-(2- methyl-1,3-thiazol-...)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717198BDBM717198(3-[3-(4-fluorophenyl)-4-{6-[4- (4-methylpiperazin-...)
Affinity DataIC50: 0.170nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717192BDBM717192(3-[3-(4-fluorophenyl)-4-{2-[4- (4-methylpiperazin-...)
Affinity DataIC50: 0.173nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717237BDBM717237(1-[3-(4-fluorophenyl)-4-(6- phenylfuro[2,3-d]pyrim...)
Affinity DataIC50: 0.177nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717421BDBM717421(3-{4-[6-(1,3-dimethyl-1H- pyrazol-4-yl)furo[2,3- d...)
Affinity DataIC50: 0.180nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717288BDBM717288(1-[3-(2-fluorophenyl)-4-(6- phenylfuro[2,3-d]pyrim...)
Affinity DataIC50: 0.180nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717305BDBM717305((3S)-3-{[3-(4-fluorophenyl)-4- (6-phenylfuro[2,3-d...)
Affinity DataIC50: 0.180nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717369BDBM717369(3-[3-(4-fluorophenyl)-4-(6-{3- [(morpholin-4- yl)m...)
Affinity DataIC50: 0.180nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717446BDBM717446(1-[4-{6-[5-(difluoromethyl)-1- methyl-1H-pyrazol-4...)
Affinity DataIC50: 0.185nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717435BDBM717435(4-{3-(4-fluorophenyl)-1-[(1s,3s)- 3-(methanesulfon...)
Affinity DataIC50: 0.190nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717219BDBM717219(3-[3-(4-fluorophenyl)-4-(6- phenylfuro[2,3-d]pyrim...)
Affinity DataIC50: 0.192nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 717430BDBM717430(1-{4-[6-(1,3-dimethyl-1H- pyrazol-4-yl)furo[2,3- d...)
Affinity DataIC50: 0.200nMAssay Description:The inhibitory activity of the compounds disclosed herein were measured in a biochemical assay utilizing a recombinant human EGFR exon 19 deletion/C7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

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