Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Eyes absent homolog 3 [223-510]'
TargetEyes absent homolog 3 [223-510](Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM18964(NSC85438 | 4-[(2-butyl-1-benzofuran-3-yl)carbonyl]...)
Affinity DataIC50: 1.01E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetEyes absent homolog 3 [223-510](Mouse)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM18964(NSC85438 | 4-[(2-butyl-1-benzofuran-3-yl)carbonyl]...)
Affinity DataIC50: 1.01E+4nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetEyes absent homolog 3 [223-510](Mouse)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 1.10E+4nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetEyes absent homolog 3 [223-510](Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 1.10E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetEyes absent homolog 3 [223-510](Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342278((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...)
Affinity DataIC50: 1.92E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetEyes absent homolog 3 [223-510](Mouse)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342278((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...)
Affinity DataIC50: 1.92E+4nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent