Compile Data Set for Download or QSAR
Report error Found 1761 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1'
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156370BDBM50156370(CHEMBL3793436)
Affinity DataEC50:  0.0570nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156370BDBM50156370(CHEMBL3793436)
Affinity DataEC50:  0.0620nMAssay Description:Agonist activity at mouse TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399971BDBM50399971(CHEMBL2181247)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019474BDBM50019474(CHEMBL3290717)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266580BDBM50266580(CHEMBL4087611)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429128BDBM50429128(CHEMBL2336232)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399970BDBM50399970(CHEMBL2181229)
Affinity DataEC50:  0.310nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552649BDBM50552649(CHEMBL4779837)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266544BDBM50266544(CHEMBL4060410)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612411BDBM50612411(CHEMBL5270816)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at TGR5 in human HEK293 cells assessed as increase in cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019475BDBM50019475(CHEMBL3290716)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399969BDBM50399969(CHEMBL2181227)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 398287BDBM398287(US10323016, Example 26)
Affinity DataEC50:  0.5nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003570BDBM50003570(CHEMBL3234869)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612414BDBM50612414(CHEMBL5285528)
Affinity DataEC50: <0.5nMAssay Description:Agonist activity at TGR5 in human HEK293 cells assessed as increase in cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003559BDBM50003559(CHEMBL3234570)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399968BDBM50399968(CHEMBL2181228)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614538BDBM50614538(CHEMBL5286836)
Affinity DataEC50:  0.710nMAssay Description:Inhibition of mouse TGR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399967BDBM50399967(CHEMBL2181230)
Affinity DataEC50:  0.720nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399966BDBM50399966(CHEMBL2181226)
Affinity DataEC50:  0.720nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266538BDBM50266538(US10323016, Example 4 | CHEMBL4084668)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266552BDBM50266552(US10323016, Example 20 | CHEMBL4094487)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565258BDBM50565258(CHEMBL4779084)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019474BDBM50019474(CHEMBL3290717)
Affinity DataEC50:  0.920nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399970BDBM50399970(CHEMBL2181229)
Affinity DataEC50:  0.980nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612402BDBM50612402(CHEMBL5290871)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TGR5 transfected in CHO cells assessed as increase in cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459101BDBM50459101(CHEMBL4213913)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266538BDBM50266538(US10323016, Example 4 | CHEMBL4084668)
Affinity DataEC50:  1nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003573BDBM50003573(CHEMBL3234871)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266552BDBM50266552(US10323016, Example 20 | CHEMBL4094487)
Affinity DataEC50:  1nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003407BDBM50003407(CHEMBL3234568)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003559BDBM50003559(CHEMBL3234570)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003569BDBM50003569(CHEMBL3234868)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415407BDBM50415407(CHEMBL612138)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552647BDBM50552647(CHEMBL4790044)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552646BDBM50552646(CHEMBL4743463)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459099BDBM50459099(CHEMBL4202981)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429126BDBM50429126(CHEMBL2336233)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429129BDBM50429129(CHEMBL2336231)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459099BDBM50459099(CHEMBL4202981)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612418BDBM50612418(CHEMBL5284434)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells measured after 5.5 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019478BDBM50019478(CHEMBL3290715)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399962BDBM50399962(CHEMBL2181239)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019479BDBM50019479(CHEMBL3290713)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160886BDBM50160886(CHEMBL3794442)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272009BDBM50272009(CHEMBL4126062)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428105BDBM50428105(CHEMBL2331649)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019485BDBM50019485(CHEMBL3290720)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429127BDBM50429127(CHEMBL2331604)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459141BDBM50459141(CHEMBL4212707)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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