Report error Found 459 Enz. Inhib. hit(s) with Target = 'Glyceraldehyde-3-phosphate dehydrogenase'
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against Trypanosoma mexicana glyceraldehyde-3-phosphate dehydrogenase (GAPDH)More data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to human GAPDH incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
TargetGlyceraldehyde-3-phosphate dehydrogenase, glycosomal(Trypanosoma cruzi)
Universidade De S£O Paulo
Curated by ChEMBL
Universidade De S£O Paulo
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (GAPDH)More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration of compound against glyceraldehyde-3-phosphate dehydrogenase was determinedMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase (GAPDH)More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Cell culture: Cells were cultured in RPMI1640 medium+15% FBS. Cells were maintained at a density between 2e5/mL and 1e6/mL. Cells were centrifuged, r...More data for this Ligand-Target Pair
