Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with Target = 'Hemagglutinin'
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596582(CHEMBL5202013)
Affinity DataKd:  0.00700nMAssay Description:Binding affinity to Influenza A Puerto Rico/8/1934/H1N1 hemagglutin assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596583(CHEMBL5183382)
Affinity DataKd:  0.00700nMAssay Description:Binding affinity to Influenza A Puerto Rico/8/1934/H1N1 hemagglutin assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493569(US10987354, Example 33)
Affinity DataEC50:  0.0100nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493573(US10987354, Example 62)
Affinity DataEC50:  0.0110nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493568(US10987354, Example 29)
Affinity DataEC50:  0.0130nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493563(US10987354, Example 13)
Affinity DataEC50:  0.0170nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493566(US10987354, Example 27)
Affinity DataEC50:  0.0240nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493574(US10987354, Example 63)
Affinity DataEC50:  0.0790nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493539(US10987354, Example 4)
Affinity DataEC50:  0.116nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493565(US10987354, Example 20)
Affinity DataEC50:  0.192nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611021(US10626108, Compound 15)
Affinity DataIC50: 0.200nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493576(US10987354, Example 66)
Affinity DataEC50:  0.274nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493544(US10987354, Example 8)
Affinity DataEC50:  0.394nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493543(US10987354, Example 6)
Affinity DataEC50:  0.398nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493571(US10987354, Example 49)
Affinity DataEC50:  0.521nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493534(US10987354, Example 3)
Affinity DataEC50:  0.672nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493572(US10987354, Example 55)
Affinity DataEC50:  0.680nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493564(US10987354, Example 15)
Affinity DataEC50:  0.760nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493575(US10987354, Example 64)
Affinity DataEC50:  0.887nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (A/Shangdong/9/93(H3N2)))
Gilead Sciences

LigandPNGBDBM4934((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/mole IC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2005
Entry Details Article

TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611022(US10626108, Compound 21)
Affinity DataIC50: 1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611015(US10626108, Compound 13)
Affinity DataIC50: 1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50524786(CHEMBL4467587)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to influenza A virus hemagglutin by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493570(US10987354, Example 39)
Affinity DataEC50:  1.22nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (A/reassortant/NIBRG-121(Califor...)
SociÉTÉ

US Patent
LigandPNGBDBM525152(US10988505, Example 2 | N-0385 | Ms-QFR-kbt)
Affinity DataEC50:  1.56nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611029(US10626108, Compound 29)
Affinity DataIC50: 2nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5023((1R,3R,4R)-3-carbamimidamido-4-[(1S)-1-acetamido-2...)
Affinity DataIC50: 2nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2005
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611020(US10626108, Compound 14)
Affinity DataIC50: 2nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (A/reassortant/NIBRG-121(Califor...)
SociÉTÉ

US Patent
LigandPNGBDBM525153(US10988505, Example 3 | N-0386 | Ac-QFR-kbt)
Affinity DataEC50:  2.28nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493562(US10987354, Example 12)
Affinity DataEC50:  2.54nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493540(US10987354, Example 5)
Affinity DataEC50:  3.52nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493533(US10987354, Example 1)
Affinity DataEC50:  3.89nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataIC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2005
Entry Details Article
PubMed
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM5025(ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-y...)
Affinity DataIC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2005
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611056(US10626108, Compound 36)
Affinity DataIC50: 7nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University

Curated by ChEMBL
LigandPNGBDBM50320028(GRVPVFGLSPLFKVE | CHEMBL1084191)
Affinity DataKd:  7.80nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutininin by phage ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University

Curated by ChEMBL
LigandPNGBDBM50320025(ARLSPTMVHPNGAQP | CHEMBL1084188)
Affinity DataKd:  7.80nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutininin by phage ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611028(US10626108, Compound 28)
Affinity DataIC50: 8nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/X-31 H3N2))
SociÉTÉ

US Patent
LigandPNGBDBM525152(US10988505, Example 2 | N-0385 | Ms-QFR-kbt)
Affinity DataEC50:  9.33nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University

Curated by ChEMBL
LigandPNGBDBM50320027(GRPPDSVFRSRGWLS | CHEMBL1084190)
Affinity DataKd:  11nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutininin by phage ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50512749(CHEMBL4565295)
Affinity DataKd:  16nMAssay Description:Binding affinity to hemagglutinin by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHemagglutinin(Influenza B virus (B/Victoria/70))
Biocryst Pharmaceuticals

LigandPNGBDBM4934((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Affinity DataIC50: 17nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2005
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University

Curated by ChEMBL
LigandPNGBDBM50320029(IDIAFSSLALADISR | CHEMBL1084192)
Affinity DataKd:  19nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutininin by phage ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHemagglutinin(Influenza A virus (strain A/X-31 H3N2))
SociÉTÉ

US Patent
LigandPNGBDBM525151(US10988505, Example 1)
Affinity DataEC50:  20.9nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Taiwan/1/1986 H1N1))
Janssen Sciences Ireland Uc

US Patent
LigandPNGBDBM611026(US10626108, Compound 25)
Affinity DataIC50: 26nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (A/reassortant/NIBRG-121(Califor...)
SociÉTÉ

US Patent
LigandPNGBDBM525151(US10988505, Example 1)
Affinity DataEC50:  27.3nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Aichi/2/1968 H3N2))
Individual

US Patent
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | CHEMBL959 ...)
Affinity DataIC50: 30nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University

Curated by ChEMBL
LigandPNGBDBM50320026(EPYGFIAFSRAAHSP | CHEMBL1084189)
Affinity DataKd:  30nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutininin by phage ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHemagglutinin/Neuraminidase(Influenza A virus (A/Weiss/1943(H1N1)))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM493532(US10987354, Control Compound A)
Affinity DataEC50:  33.2nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetHemagglutinin(Influenza A virus (strain A/X-31 H3N2))
SociÉTÉ

US Patent
LigandPNGBDBM525153(US10988505, Example 3 | N-0386 | Ac-QFR-kbt)
Affinity DataEC50:  34nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details
US Patent

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