Report error Found 1627 Enz. Inhib. hit(s) with Target = 'Hexokinase-4'
Affinity DataIC50: 0.488nMAssay Description:Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataEC50: <0.850nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 3.80nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
Affinity DataEC50: 3.90nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
Affinity DataEC50: 4.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
Affinity DataEC50: 4.80nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.20nMAssay Description:Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E. coli, and purified on ANTIFLAG M2 AFFINITY GEL (Sigma). The assay wa...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
