Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Histidine--tRNA ligase, cytoplasmic'
TargetHistidine--tRNA ligase, cytoplasmic(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091516([(S)-2-Amino-3-(1H-imidazol-4-yl)-propionyl]-sulfa...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against cognate Staphylococcus aureus Histidyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetHistidine--tRNA ligase, cytoplasmic(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  4.64E+4nMAssay Description:Binding affinity to human HARS incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed