Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 4 [648-1032]'
TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243173((R)-N-(1-(5-Azaspiro[2.5]octan-5- yl)propan-2-yl)-...)
Affinity DataIC50: 3nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243152(D1: N-((R)-1-((abs)-3- (Difluoromethoxy)piperidin-...)
Affinity DataIC50: 3nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243193(D1: N-((R)-1-((abs-1,5-cis)-6- Azabicyclo[3.2.0]he...)
Affinity DataIC50: 4nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243192(N-((2R)-1-(3-Azabicyclo[3.2.0]heptan- 3-yl)propan-...)
Affinity DataIC50: 4nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243189((R)-N-(1-(3,4-dihydro-2,7-naphthyridin- 2(1H)-yl)p...)
Affinity DataIC50: 6nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243183(N-((R)-1-(3-Azabicyclo[3.2.1]octan-3- yl)propan-2-...)
Affinity DataIC50: 7nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243091(N-((2R)-1-(3-Azabicyclo[3.1.0]hexan-3- yl)propan-2...)
Affinity DataIC50: 8nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243180((R)-N-(1-(5-Azaspiro[2.4]heptan-5- yl)propan-2-yl)...)
Affinity DataIC50: 8nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243202((2S)-1-((R)-2-(3-Fluoro-4-(5- (trifluoromethyl)-1,...)
Affinity DataIC50: 9nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243121((R)-N-(1-(3,4-Dihydroisoquinolin- 2(1H)-yl)propan-...)
Affinity DataIC50: 9nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243178((R)-N-(1-(Azepan-1-yl)propan-2-yl)-4- (5-(trifluor...)
Affinity DataIC50: 11nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243187(2-((R)-2-(4-(5-(Trifluoromethyl)-1,2,4- oxadiazol-...)
Affinity DataIC50: 12nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243123((R)-N-(1-(3-Phenylazetidin-1-yl)propan- 2-yl)-4-(5...)
Affinity DataIC50: 14nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243179((R)-N-(1-(1-Azaspiro[3.3]heptan-1- yl)propan-2-yl)...)
Affinity DataIC50: 16nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243201(N-((2R)-1-(6,6-Dimethyl-3- azabicyclo[3.1.0]hexan-...)
Affinity DataIC50: 20nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243152(D1: N-((R)-1-((abs)-3- (Difluoromethoxy)piperidin-...)
Affinity DataIC50: 21nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243193(D1: N-((R)-1-((abs-1,5-cis)-6- Azabicyclo[3.2.0]he...)
Affinity DataIC50: 22nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243176((R)-N-(1-(6-Azaspiro[2.5]octan-6- yl)propan-2-yl)-...)
Affinity DataIC50: 30nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM242586((R)-N-(1-(Isoindolin-2-yl)propan-2-yl)- 4-(5-(trif...)
Affinity DataIC50: 39nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243093((S)-N-(1-Cyclopropyl-2-(pyrrolidin-1- yl)ethyl)-4-...)
Affinity DataIC50: 48nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243111((R)-N-(1-Cyclopropyl-2-(pyrrolidin-1- yl)ethyl)-4-...)
Affinity DataIC50: 77nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM242582((2S)-2-Methyl-1-((R)-2-(3-methyl-4-(5- (trifluorom...)
Affinity DataIC50: 100nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM243203(N-((R)-1-((S)-2-Methylpyrrolidin-1- yl)propan-2-yl...)
Affinity DataIC50: 134nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [648-1032](Human)
Chdi Foundation

US Patent
LigandPNGBDBM242584(N-(2-(3-Azabicyclo[3.2.1]octan-3- yl)ethyl)-4-(5-(...)
Affinity DataIC50: 140nMAssay Description:5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent