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Report error Found 157 Enz. Inhib. hit(s) with Target = 'Homeodomain-interacting protein kinase 1'
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50400734(CHEMBL1591531)
Affinity DataIC50: 0.367nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataKi: <10nMAssay Description:Inhibition of wild-type human partial length HIPK1 (M146 to I555 residues) expressed in mammalian expression system assessed as residual activity at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563555(CHEMBL4750420)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563556(CHEMBL4743939)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM124970(US8765747, 2)
Affinity DataKd:  34nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50172243(CHEMBL3103192)
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk1 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563541(CHEMBL4743730)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  55nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563554(CHEMBL4790030)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd:  93nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563539(CHEMBL4762964)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50248614(CHEMBL4066819)
Affinity DataKd:  160nMAssay Description:Binding affinity to partial length human HIPK1 (M146 to I555 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  170nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563537(CHEMBL4789951)
Affinity DataIC50: 177nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50560704(CHEMBL4754195)
Affinity DataIC50: 187nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50560704(CHEMBL4754195)
Affinity DataIC50: 187nMAssay Description:Inhibition of human HIPK1 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563538(CHEMBL4797457)
Affinity DataIC50: 209nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563540(CHEMBL4740998)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  230nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  230nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563557(CHEMBL4790791)
Affinity DataIC50: 235nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: 248nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563535(CHEMBL4791451)
Affinity DataIC50: 264nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563544(CHEMBL4778370)
Affinity DataIC50: 278nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563534(CHEMBL4778153)
Affinity DataIC50: 285nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  300nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataKd:  320nMAssay Description:Binding affinity to HIPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563536(CHEMBL4741919)
Affinity DataIC50: 354nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50355504(CHEMBL1908393)
Affinity DataKd:  420nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  430nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)
Affinity DataKd:  510nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  520nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563551(CHEMBL4777533)
Affinity DataIC50: 545nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  590nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  590nMAssay Description:Binding affinity to HIPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 621nMAssay Description:Inhibition of human HIPK1 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563543(CHEMBL4794825)
Affinity DataIC50: 685nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 798nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  820nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  860nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563542(CHEMBL4789373)
Affinity DataIC50: 921nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  970nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human wild type HIPK1 using RBER-CHKtide as substrate preincubated for 2 hrs followed by ATP addition and measured every 2 mins for 2.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
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