Compile Data Set for Download or QSAR
Report error Found 175 Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 1'
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338536([({[(2S,3R,4S,5S)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  1nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19263([({[(2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338539(Mycophenolic 2-ethyladenosin-5'-yl-difluoromethyle...)
Affinity DataKi:  5nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19257({[(2R,3S,4R,5R)-5-(4-carbamoyl-1,3-thiazol-2-yl)-3...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19261([({[(2R,3S,4R,5R)-5-(6-amino-2-ethynyl-9H-purin-9-...)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338537(Tiazofurin-5'-yl-2-ethyladenosin-5'-yl-diflurometh...)
Affinity DataKi:  13nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338538({[(2S,3R,4S,5S)-5-(6-Amino-2-ethyl-purin-9-yl)-3,4...)
Affinity DataKi:  16nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19267([({[(2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19255([({[(2R,3S,4R,5R)-5-(6-amino-2-iodo-9H-purin-9-yl)...)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19267([({[(2R,3S,4R,5R)-5-(6-amino-2-ethyl-9H-purin-9-yl...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19256([({[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50192467(P1-[7-hydroxy-6-(ethyl-2-yl)-5-methoxy-4-methylpht...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338541(((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dih...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  33nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I isoform); Range is 33-37 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  33nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMPDH 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112565(N-tert-Butyl-N'-(3-methoxy-4-oxazol-5-yl-phenyl)-o...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19258([({[(2R,3S,4R,5R)-5-[6-amino-2-(phenylamino)-9H-pu...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19259([({[(2R,3S,4R,5R)-5-[6-amino-2-(benzylamino)-9H-pu...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  62nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19266([({[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  66nM ΔG°:  -41.0kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19266([({[(2R,3S,4R,5R)-5-(6-amino-2-phenyl-9H-purin-9-y...)
Affinity DataKi:  70nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338552(6-(-4-(4-((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  70nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50228085(N-hydroxy-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataKi:  70nMAssay Description:Inhibition of human IMPDH 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50322459(6-((E)-4-(4-(Adenosin-50-yl)methyl-1H-1,2,3-triazo...)
Affinity DataKi:  70nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19260([({[(2R,3S,4R,5R)-5-{6-amino-2-[(2-phenylethyl)ami...)
Affinity DataKi:  73nM ΔG°:  -40.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338553(6-(-4-((1-(((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  77nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50322457(6-((E)-4-(((1-(50-Deoxy-adenosin-50-yl)-1H-1,2,3-t...)
Affinity DataKi:  77nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338540(((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataKi:  87nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50192469(P1-(adenosin-5'-yl)methylenephospho-P2-[7-hydroxy-...)
Affinity DataKi:  87nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338550(Mycophenolic ethylenephosphonate-5'-thioadenosine ...)
Affinity DataKi:  94nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338542(Mycophenolic adenosin-5'-yl-ethylenebis(phosphonat...)
Affinity DataKi:  95nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19262([({[(2R,3S,4R,5R)-5-(6-amino-2-ethenyl-9H-purin-9-...)
Affinity DataKi:  96nM ΔG°:  -40.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2007
Entry Details Article
PubMed
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