Compile Data Set for Download or QSAR
Report error Found 366 Enz. Inhib. hit(s) with Target = 'Inositol hexakisphosphate kinase 1'
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647694(CHEMBL5598155)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647666(CHEMBL5598038)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647707(CHEMBL5596194)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647716(CHEMBL5590726)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647712(CHEMBL5598068)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647719(CHEMBL5598514)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647685(CHEMBL5597913)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647693(CHEMBL5596094)
Affinity DataIC50: 8nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inhibition of [3H]-InsP6 phosphorylation m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647687(CHEMBL5598435)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739877(US20250154115, Compound 85)
Affinity DataIC50: 10nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739920(US20250154115, Compound 130)
Affinity DataIC50: 10nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647706(CHEMBL5597090)
Affinity DataIC50: 16nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647720(CHEMBL5590042)
Affinity DataIC50: 16nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605488(CHEMBL5169462 | US20250154115, Compound 57)
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605484(CHEMBL5181623 | US20250154115, Compound 16)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647690(CHEMBL5598271)
Affinity DataIC50: 27nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605510(CHEMBL5203174 | US20250197396, Compound 2a)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant full length human IP6K1 assessed as inorganic phosphate release measured after 30 mins by ADP-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647655(CHEMBL5596469)
Affinity DataIC50: 28nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647672(CHEMBL5597088)
Affinity DataIC50: 28nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647708(CHEMBL5596929)
Affinity DataIC50: 30nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647658(US20250197396, Compound 16a)
Affinity DataIC50: 31nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647696(CHEMBL5596184)
Affinity DataIC50: 35nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647675(CHEMBL5596237)
Affinity DataIC50: 36nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647686(CHEMBL5596303)
Affinity DataIC50: 39nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50647697(CHEMBL5597391)
Affinity DataIC50: 43nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739882(US20250154115, Compound 90)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739881(US20250154115, Compound 89)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739880(US20250154115, Compound 88)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739886(US20250154115, Compound 94)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739884(US20250154115, Compound 92)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739883(US20250154115, Compound 91)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605488(CHEMBL5169462 | US20250154115, Compound 57)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605484(CHEMBL5181623 | US20250154115, Compound 16)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739876(US20250154115, Compound 84)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739875(US20250154115, Compound 83)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM50605509(CHEMBL5204881 | US20250154115, Compound 19)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739879(US20250154115, Compound 87)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739878(US20250154115, Compound 86)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739809(US20250154115, Compound 17)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739856(US20250154115, Compound 64)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739902(US20250154115, Compound 112)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739901(US20250154115, Compound 111)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739900(US20250154115, Compound 110)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739899(US20250154115, Compound 109)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739855(US20250154115, Compound 63)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739858(US20250154115, Compound 66)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandPNGBDBM739908(US20250154115, Compound 118)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

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