Compile Data Set for Download or QSAR
Report error Found 178 Enz. Inhib. hit(s) with Target = 'Inositol hexakisphosphate kinase 2'
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inhibition of [3H]-Ins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739920(US20250154115, Compound 130)
Affinity DataIC50: 10nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605510(CHEMBL5203174 | US20250197396, Compound 2a)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant full length human IP6K2 assessed as inorganic phosphate release measured after 30 mins by ADP-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605488(CHEMBL5169462 | US20250154115, Compound 57)
Affinity DataIC50: 54nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inorganic phosphate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739882(US20250154115, Compound 90)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739864(US20250154115, Compound 72)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739881(US20250154115, Compound 89)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739919(US20250154115, Compound 129)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739885(US20250154115, Compound 93)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739866(US20250154115, Compound 74)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739884(US20250154115, Compound 92)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739883(US20250154115, Compound 91)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605488(CHEMBL5169462 | US20250154115, Compound 57)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739865(US20250154115, Compound 73)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605484(CHEMBL5181623 | US20250154115, Compound 16)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739876(US20250154115, Compound 84)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739860(US20250154115, Compound 68)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739915(US20250154115, Compound 125)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605483(CHEMBL5184960 | US20250154115, Compound 15)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739918(US20250154115, Compound 128)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739879(US20250154115, Compound 87)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605491(CHEMBL5186210 | US20250154115, Compound 54)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739917(US20250154115, Compound 127)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739878(US20250154115, Compound 86)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739809(US20250154115, Compound 17)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739861(US20250154115, Compound 69)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739877(US20250154115, Compound 85)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739856(US20250154115, Compound 64)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739872(US20250154115, Compound 80)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739855(US20250154115, Compound 63)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739929(US20250154115, Compound 139)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739858(US20250154115, Compound 66)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739874(US20250154115, Compound 82)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605508(CHEMBL5200214 | US20250154115, Compound 30)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739857(US20250154115, Compound 65)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739873(US20250154115, Compound 81)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739889(US20250154115, Compound 97)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739868(US20250154115, Compound 76)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739888(US20250154115, Compound 96)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739887(US20250154115, Compound 95)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739851(US20250154115, Compound 59)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739886(US20250154115, Compound 94)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739928(US20250154115, Compound 138)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM739869(US20250154115, Compound 77)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605491(CHEMBL5186210 | US20250154115, Compound 54)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inorganic phosphate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605508(CHEMBL5200214 | US20250154115, Compound 30)
Affinity DataIC50: 71nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inorganic phosphate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605484(CHEMBL5181623 | US20250154115, Compound 16)
Affinity DataIC50: 74nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inorganic phosphate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataKd:  74nMAssay Description:Binding affinity to MBP-tagged recombinant human IP6K2 at 400 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50605483(CHEMBL5184960 | US20250154115, Compound 15)
Affinity DataIC50: 94nMAssay Description:Inhibition of N-terminal 6His-tagged/TEV cleavage site fused recombinant human IP6K2 expressed in Escherichia coli assessed as inorganic phosphate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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