Compile Data Set for Download or QSAR
Report error Found 241 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF18A [1-467]'
TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762886(2-Hydroxy-N-(4-(5-(6-methyl-2-(3,3,3-trifluoroprop...)
Affinity DataIC50: 1nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762888(N-(4-(5-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 1nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762896(N-(4-(5-(2-(6,6-Difluoro-3-azabicyclo[3.1.0]hexan-...)
Affinity DataIC50: 1nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762883(N-(4-(5-(2-(3,3-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 1nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762918(N-(4-(4-(2-(3,3-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762890(N-(4-(5-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762906(N-(4-(5-(2-(4-Fluoropiperidin-1-yl)-6-methylpyridi...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762910(N-(4-(4-(2-(4,4-Difluorocyclohexyl)-6-methylpyrimi...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762880(N-(4-(5-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762912(US20250250264, Compound I-112)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762897(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-6-ethylpyr...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762884(N-(4-(5-(2-(4-fluoropiperidin-1-yl)-6-methylpyrimi...)
Affinity DataIC50: 2nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762919(N-(4-(4-(1-(3,3-Difluorocyclobutyl)-6-oxo-1,6-dihy...)
Affinity DataIC50: 3nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762894(N-(4-(5-(2-(3-azabicyclo[3.1.0]hexan-3-yl)-6-methy...)
Affinity DataIC50: 3nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762899(N-(4-(5-(6-Methyl-2-(3,3,3-trifluoropropoxy)pyrimi...)
Affinity DataIC50: 3nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762903(N-(4-(5-(2-(3-Fluoropiperidin-1-yl)-6-methylpyrimi...)
Affinity DataIC50: 4nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM636903(US20230382889, Compound 47 | N-(4-(4-(2-(4,4-diflu...)
Affinity DataIC50: 4nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762895(N-(4-(5-(6-(4,4-Difluoropiperidin-1-yl)-4-methylpy...)
Affinity DataIC50: 4nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762921(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 5nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762909(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)pyrimidin-4...)
Affinity DataIC50: 5nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762911(US20250250264, Compound I-111)
Affinity DataIC50: 5nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762915(N-(4-(4-(6-Methyl-2-(3,3,3-trifluoropropoxy)pyrimi...)
Affinity DataIC50: 5nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762913(N-(4-(4-(2-(6,6-Difluoro-3-azabicyclo[3.1.0]hexan-...)
Affinity DataIC50: 7nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762882(N-(4-(5-(2-(3,3-Difluoropyrrolidin-1-yl)-6-methylp...)
Affinity DataIC50: 7nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762914(N-(4-(4-(2-(4-Fluoropiperidin-1-yl)-6-methylpyrimi...)
Affinity DataIC50: 7nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762901(N-(4-(5-(2-((3S,4R)-3,4-Difluoropyrrolidin-1-yl)-6...)
Affinity DataIC50: 8nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762908(N-(4-(4-(2-(Difluoromethyl)-6-(4,4-difluoropiperid...)
Affinity DataIC50: 8nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762922(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-5-fluoropy...)
Affinity DataIC50: 9nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762923(N-(4-(4-(4-(4,4-Difluoropiperidin-1-yl)-1,3,5-tria...)
Affinity DataIC50: 9nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762917(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 9nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762885(2-Hydroxy-N-(4-(5-(6-methyl-2-(5-azaspiro[2.4]hept...)
Affinity DataIC50: 10nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762900(N-(4-(5-(6-Methyl-2-(3,3,5,5-tetrafluoropiperidin-...)
Affinity DataIC50: 10nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762887(US20250250264, Compound I-40)
Affinity DataIC50: 11nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762907(N-(3-(4,4-Difluoropiperidin-1-yl)-4-(4-(2-(4,4-dif...)
Affinity DataIC50: 11nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762892(N-(4-(4-(2-(4,4-Difluoropiperidin-1-yl)-6-methylpy...)
Affinity DataIC50: 11nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762881(N-(4-(5-(2-(3,3-Difluoroazetidin-1-yl)-6-methylpyr...)
Affinity DataIC50: 11nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762904(N-(4-(5-(4-Methyl-6-(3-(trifluoromethyl)piperidin-...)
Affinity DataIC50: 12nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762905(N-(4-(5-(4-Methyl-6-(3-(trifluoromethyl)pyrrolidin...)
Affinity DataIC50: 13nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762916(N-(4-(4-(6-Methyl-2-(pyrrolidin-1-yl)pyrimidin-4-y...)
Affinity DataIC50: 13nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM535532(N-(2-(4,4-Difluoropiperidin-1-yl)-6- methylpyrimid...)
Affinity DataIC50: 17nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM50561924(US11236069, Example 6-29 | CHEMBL4750775)
Affinity DataIC50: 17nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM50561923(US11236069, Example 6-24-1 | CHEMBL4751673)
Affinity DataIC50: 17.4nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM50561926(US11236069, Example 11-25 | CHEMBL4776120)
Affinity DataIC50: 17.6nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM50561925(US11236069, Example 11-4 | CHEMBL4743241)
Affinity DataIC50: 18nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM762898(N-(4-(5-(6-methyl-2-(3-(trifluoromethyl)pyrrolidin...)
Affinity DataIC50: 18nMAssay Description:The reaction system consisted of a test compound, the recombinant protein KIF18A (aa 1-467), ATP (Promega Inc), and an assay buffer. The test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM50561927(US11236069, Example 11-62 | CHEMBL4740783)
Affinity DataIC50: 18nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM535640(N-(2-(4-Fluoropiperidin-1-yl)- 6-methylpyrimidin-4...)
Affinity DataIC50: 20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM535665((R)-N-(2-(3,3-Difluoroazetidin- 1-yl)-6-methylpyri...)
Affinity DataIC50: 20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM535616((R)-N-(2-(3-Fluoro-3- methylpyrrolidin-1-yl)-6- me...)
Affinity DataIC50: 20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetKinesin-like protein KIF18A [1-467](Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM535618(N-(2-((1R,5S)-3- Azabicyclo[3.1.0]hexan-3-yl)- 6-m...)
Affinity DataIC50: 20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

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