Compile Data Set for Download or QSAR
Report error Found 184 Enz. Inhib. hit(s) with Target = 'Long-chain-fatty-acid--CoA ligase 5'
TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768266((R)-2,3-difluoro-N-((4-((1-methylpiperidin-4-yl)ox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768265((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768268((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768267((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768262((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768264(4-((R)-1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768263((R)-N-((4-((1-azabicyclo[2.2.1]heptan-4-yl)oxy)phe...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768258((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768257((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768260((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768259((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768254((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768253(N-((4-(((1R,4R,5R)-2-azabicyclo[2.2.1]heptan-5-yl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768256((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768255((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768282((R)-2,3-difluoro-N-((1-methylpiperidin-4-yl)sulfon...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768281((R)-2,3-difluoro-4-(1-(5-(pyridin-2-yloxy)pyridin-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768283((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768278((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768277((R)-N-((4-(2-(dimethylamino)ethoxy)piperidin-1-yl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768279((R)-2,3-difluoro-N-((4-methylpiperazin-1-yl)sulfon...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768273((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768270((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768269((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768272((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768271((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768298(4-((R)-1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768297((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768300((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768299((R)-N-((4-(2-(dimethylamino)ethoxy)phenyl)sulfonyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768294(4-((R)-1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768293((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768295(2,3-difluoro-N-((4-((1-methylpiperidin-3-yl)oxy)ph...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768290((R)-N-((4-((1-methylpiperidin-4-yl)oxy)piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768289((R)-N-((4-(2-(dimethylamino)ethoxy)phenyl)sulfonyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768291((R)-N-((4-(2-(dimethylamino)ethoxy)phenyl)sulfonyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768286((R)-N-((1-(dimethylamino)-2-methylpropan-2-yl)sulf...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768285((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768288((R)-N-((4-(2-(dimethylamino)ethoxy)phenyl)sulfonyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768287((R)-N-((4-((1-methylpiperidin-4-yl)oxy)piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768314((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768313((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768316((R)-N-((4-cyclohexylpiperazin-1-yl)sulfonyl)-4-(1-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768315((R)-N-((4-cyclopropylpiperazin-1-yl)sulfonyl)-2,3-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768310((R)-N-((4-ethylpiperazin-1-yl)sulfonyl)-2,3-difluo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768312((R)-N-((4-methylpiperazin-1-yl)sulfonyl)-4-(1-(5-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768311((R)-4-(1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768306(N-((4-(2-(dimethylamino)ethoxy)phenyl)sulfonyl)-2,...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768305(4-((R)-1-(5-(cyclopropylmethoxy)pyridin-2-yl)propo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetLong-chain-fatty-acid--CoA ligase 5 [33-683](Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM768307(2,3-difluoro-4-((R)-1-(5-((1R,3R)-3-methoxycyclobu...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACSL5 enzyme activity was monitored with a coupled enzyme Amplex Red assay. The assay is carried out in 384-well microtiterplates. In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

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