Report error Found 134 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 4'
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 34nMAssay Description:Binding affinity to human MAP3K4 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 39nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 56nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 130nMAssay Description:Average Binding Constant for MAP3K4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 280nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 280nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 840nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.60E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.80E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.90E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.00E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.00E+3nMAssay Description:Average Binding Constant for MAP3K4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.20E+3nMAssay Description:Average Binding Constant for MAP3K4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.50E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.50E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.60E+3nMAssay Description:Binding affinity to MAP3K4More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 2.60E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 3.00E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 3.30E+3nMAssay Description:Average Binding Constant for MAP3K4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 4.10E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 4.80E+3nMAssay Description:Average Binding Constant for MAP3K4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 4.80E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 5.33E+3nMAssay Description:Binding affinity to human MAP3K4 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 5.50E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 5.50E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 5.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 5.60E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of C-terminal NanoLuc-fused full length MAP3K4 (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 6.70E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 8.40E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 8.40E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 8.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MAP3K4More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 4(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair

































