Compile Data Set for Download or QSAR
Report error Found 136 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 2 group E member 1'
TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655839(US20240067625, Compound 95)
Affinity DataEC50:  0.00300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655838(US20240067625, Compound 94)
Affinity DataEC50:  0.00300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655840(US20240067625, Compound 96)
Affinity DataEC50:  0.00300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655837(US20240067625, Compound 93)
Affinity DataEC50:  0.00400nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655830(US20240067625, Compound 70)
Affinity DataEC50:  0.00500nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655812(US20240067625, Compound 41)
Affinity DataEC50:  0.00600nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655832(US20240067625, Compound 72)
Affinity DataEC50:  0.00700nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655835(US20240067625, Compound 75)
Affinity DataEC50:  0.00800nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655833(US20240067625, Compound 73)
Affinity DataEC50:  0.00800nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655829(US20240067625, Compound 69)
Affinity DataEC50:  0.00800nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655821(US20240067625, Compound 53)
Affinity DataEC50:  0.00900nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655828(US20240067625, Compound 64)
Affinity DataEC50:  0.00900nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655834(US20240067625, Compound 74)
Affinity DataEC50:  0.0100nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655817(US20240067625, Compound 48)
Affinity DataEC50:  0.0100nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655815(US20240067625, Compound 45)
Affinity DataEC50:  0.0110nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655814(US20240067625, Compound 44)
Affinity DataEC50:  0.0120nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655827(US20240067625, Compound 63)
Affinity DataEC50:  0.0120nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655826(US20240067625, Compound 62)
Affinity DataEC50:  0.0120nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655807(US20240067625, Compound 35)
Affinity DataEC50:  0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655808(US20240067625, Compound 36)
Affinity DataEC50:  0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655836(US20240067625, Compound 76)
Affinity DataEC50:  0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655816(US20240067625, Compound 47)
Affinity DataEC50:  0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655805(US20240067625, Compound 32)
Affinity DataEC50:  0.0140nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655804(US20240067625, Compound 31)
Affinity DataEC50:  0.0140nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655825(US20240067625, Compound 61)
Affinity DataEC50:  0.0150nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655806(US20240067625, Compound 33)
Affinity DataEC50:  0.0190nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655819(US20240067625, Compound 51)
Affinity DataEC50:  0.0200nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655820(US20240067625, Compound 52)
Affinity DataEC50:  0.0260nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655800(US20240067625, Compound 3)
Affinity DataEC50:  0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655810(US20240067625, Compound 39)
Affinity DataEC50:  0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655800(US20240067625, Compound 3)
Affinity DataEC50:  0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655801(US20240067625, Compound 4)
Affinity DataEC50:  0.0300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655801(US20240067625, Compound 4)
Affinity DataEC50:  0.0300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655818(US20240067625, Compound 49)
Affinity DataEC50:  0.0330nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655809(US20240067625, Compound 37)
Affinity DataEC50:  0.0340nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655802(US20240067625, Compound 29)
Affinity DataEC50:  0.0360nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655822(US20240067625, Compound 55)
Affinity DataEC50:  0.0410nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655823(US20240067625, Compound 56)
Affinity DataEC50:  0.0440nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655798(US20240067625, Compound 1)
Affinity DataEC50:  0.0510nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655811(US20240067625, Compound 40)
Affinity DataEC50:  0.0530nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655799(US20240067625, Compound 2)
Affinity DataEC50:  0.0640nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM50584384(CHEMBL5090226 | US20240067625, Compound 30)
Affinity DataEC50:  0.0670nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655824(US20240067625, Compound 57)
Affinity DataEC50:  0.0750nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655798(US20240067625, Compound 1)
Affinity DataEC50:  0.0850nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM655799(US20240067625, Compound 2)
Affinity DataEC50:  0.102nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM50649615(CHEMBL5618909)
Affinity DataKd:  60nMAssay Description:Binding affinity to human TLX LBD assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM50649609(CHEMBL5618548)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human TLX LBD expressed in HEK293T cells co-transfected with RL/Gal4-VP16 assessed as repression of VP16-induced reporter activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM50649612(CHEMBL5618740)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human TLX LBD expressed in HEK293T cells co-transfected with RL/Gal4-VP16 assessed as repression of VP16-induced reporter activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM50649595(CHEMBL5619615)
Affinity DataKd:  110nMAssay Description:Binding affinity to human TLX LBD assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Baylor College of Medicine

US Patent
LigandPNGBDBM50649589(CHEMBL5619500)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human TLX LBD expressed in HEK293T cells co-transfected with RL/Gal4-VP16 assessed as repression of VP16-induced reporter activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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