Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 4 group A member 3'
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50521316(CHEMBL4560385)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of TEC (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50625067(CHEMBL5404368)
Affinity DataIC50: 18nMAssay Description:Inhibition of TEC (unknown origin) by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634283(CHEMBL5405485)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 78nMAssay Description:Inhibition of Tec (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634284(CHEMBL5427562)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50558812(CHEMBL4755698)
Affinity DataIC50: 211nMAssay Description:Inhibition of Tec (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human wild type TEC using PolyEY as substrate preincubated for 2 hrs followed by ATP addition and measured every 2 mins for 2.5 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM610463(US10774086, Example 14 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataEC50:  2.90E+3nMAssay Description:Agonist activity at NOR1 (unknown origin) by Gal4 hybrid reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50631497(CHEMBL5417665)
Affinity DataIC50: 3.80E+3nMAssay Description:Inverse agonist activity at human NOR-1 (393 to 626 residues) transfected in HEK293T cells incubated for 16 hrs by firefly/renilla based Dual-Glo luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634280(CHEMBL5397121)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50640274(CHEMBL4851009)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at human NOR-1 (393 to 626 residues) transfected in HEK293T cells incubated for 16 hrs by firefly/renilla based Dual-Glo luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50496605(CHEMBL3134411)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50002861(3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | Dayp...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50640292(CHEMBL5555816)
Affinity DataIC50: 2.90E+4nMAssay Description:Inverse agonist activity at human NOR-1 (393 to 626 residues) transfected in HEK293T cells incubated for 16 hrs by firefly/renilla based Dual-Glo luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634282(CHEMBL5428052)
Affinity DataEC50:  3.60E+4nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50640290(CHEMBL5549932)
Affinity DataIC50: 3.90E+4nMAssay Description:Inverse agonist activity at human NOR-1 (393 to 626 residues) transfected in HEK293T cells incubated for 16 hrs by firefly/renilla based Dual-Glo luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634279(CHEBI:36466 | Naphthoic acid | NAPHTHOIC ACID)
Affinity DataEC50:  5.60E+4nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634281(CHEMBL5393788)
Affinity DataEC50:  7.30E+4nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634286(CHEMBL5397040)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634287(CHEMBL5424412)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50385525(CHEMBL461681)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50371393(CHEMBL271207 | Triphenylacetic Acid | 2,2,2-triphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50634285(CHEMBL5401203)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Yangtze University

Curated by ChEMBL
LigandPNGBDBM50129030(CHEMBL81936)
Affinity DataIC50: 1.11E+5nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed