Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Nucleophosmin'
TargetNucleophosmin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to human NPM1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNucleophosmin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 10nMAssay Description:Inhibition of NPM1 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNucleophosmin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50094238(CHEMBL3589689)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of phosphorylated NPM1 recruitment to chromatic in 6 Gy irradiated human A549 cells assessed as extraction of pT199NPM1 pretreated 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetNucleophosmin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50094237(CHEMBL593574)
Affinity DataEC50:  9.70E+3nMAssay Description:Inhibition of phosphorylated NPM1 recruitment to chromatic in 6 Gy irradiated human A549 cells assessed as increase in protein solubility as extracti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetNucleophosmin(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.04E+5nMAssay Description:Binding affinity to human NPM1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed