Compile Data Set for Download or QSAR
Report error Found 1183 Enz. Inhib. hit(s) with Target = 'Nucleotide-binding oligomerization domain-containing protein 1'
LigandPNGBDBM50339301(2-Amino-6-((R)-4-carboxy-4-(didodecylamino)butanam...)
Affinity DataEC50:  0.00150nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339298(2-Amino-6-((R)-4-carboxy-4-(dodecylamino)butanamid...)
Affinity DataEC50:  0.0230nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339295(2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanamido)...)
Affinity DataEC50:  0.0270nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339304(2-Amino-6-((R)-4-amino-5-oxo-5-(undecyloxy)pentana...)
Affinity DataEC50:  0.0660nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339308(2-Amino-6-((R)-4-dodecanamido-5-ethoxy-5-oxopentan...)
Affinity DataEC50:  0.0690nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339300(2-Amino-6-((R)-4-carboxy-4-(dihexadecylamino)butan...)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339306(2-Amino-6-((R)-4-dodecanamido-5-oxo-5-(undecyloxy)...)
Affinity DataEC50:  0.134nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339310((2R)-5-((6-Amino-1,7-diethoxy-1,7-dioxoheptan-2-yl...)
Affinity DataEC50:  0.145nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339309(Diethyl 2-Amino-6-((R)-4-amino-5-oxo-5-(undecylthi...)
Affinity DataEC50:  0.181nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339299(2-Amino-6-((R)-4-carboxy-4-(dioctylamino)butanamid...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339307((15R)-10,6-Dibenzyl 15-Ethyl-2,2-dimethyl-4,12,17-...)
Affinity DataEC50:  0.238nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339317((R)-2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339312(2-Amino-6-(5-oxo-5-(undecyloxy)pentanamido)heptane...)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339311(2-Amino-6-(4-dodecanamidobutanamido)heptanedioic A...)
Affinity DataEC50:  0.504nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339296(2-((R)-4-Amino-4-carboxybutanamido)-6-dodecanamido...)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339318((S)-6-Amino-2-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50:  0.570nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339297(2-((R)-4-Carboxy-4-dodecanamidobutanamido)-6-dodec...)
Affinity DataEC50:  0.580nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339303(2-((R)-4-Carboxy-4-dodecanamidobutanamido)-6-guani...)
Affinity DataEC50:  0.622nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339305(2-Amino-6-((R)-4-amino-5-oxo-5-(undecylamino)penta...)
Affinity DataEC50:  0.826nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339319((S)-2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50:  0.960nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339302((2R)-5-((4-(2-Amino-4-oxo-4,5-dihydro-1H-imidazol-...)
Affinity DataEC50:  1.31nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339315((2R)-2-Dodecanamido-5-oxo-5-((2-oxoazepan-3-yl)ami...)
Affinity DataEC50:  1.73nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50185(2-hydroxy-4-[[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop...)
Affinity DataIC50: 20.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
LigandPNGBDBM62265(cid_709072 | MLS-0412171.0001 | 2-(4-tert-butylphe...)
Affinity DataIC50: 31.8nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM44245(methyl 2-[(4E)-1-(1,3-benzothiazol-2-yl)-4-[1-[(4-...)
Affinity DataIC50: 39.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM52783(methyl 2-[(4E)-4-(1-anilinoethylidene)-1-(1,3-benz...)
Affinity DataIC50: 39.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM62288(cid_44229055 | MLS-0412185.0001 | 4-(3,4-dihydro-1...)
Affinity DataIC50: 39.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM62271(MLS-0378444.0001 | cid_24817336 | N-[1-(3,4-dimeth...)
Affinity DataIC50: 43.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM58651(SMR000646238 | 4-[[4-[(5Z)-5-[(4-ethylphenyl)methy...)
Affinity DataIC50: 71.8nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
LigandPNGBDBM62288(cid_44229055 | MLS-0412185.0001 | 4-(3,4-dihydro-1...)
Affinity DataIC50: 80nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
LigandPNGBDBM62288(cid_44229055 | MLS-0412185.0001 | 4-(3,4-dihydro-1...)
Affinity DataIC50: 80nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM62170(MLS-0425609.0001 | cid_1088439 | 1-(4-chlorophenyl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM62170(MLS-0425609.0001 | cid_1088439 | 1-(4-chlorophenyl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
LigandPNGBDBM62170(MLS-0425609.0001 | cid_1088439 | 1-(4-chlorophenyl...)
Affinity DataIC50: 94nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)
Affinity DataIC50: 94.9nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM62269(MLS-0384970.0001 | cid_24792090 | N-[1-(2,3-dimeth...)
Affinity DataIC50: 98.3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM50339316((R)-6-Amino-2-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339313(2-((R)-4-Carboxy-4-dodecanamidobutanamido)heptaned...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339314((R)-5-((5-Aminopentyl)amino)-2-dodecanamido-5-oxop...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NF-kappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM45060(4-[4-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylide...)
Affinity DataIC50: 105nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
LigandPNGBDBM50556245(CHEMBL4749022)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM62310(cid_44251464 | N-[1-(2-fluorophenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 146nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
LigandPNGBDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM64828(4-[4-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-...)
Affinity DataIC50: 151nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
LigandPNGBDBM54409(ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50: 152nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM54484(N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazo...)
Affinity DataEC50:  170nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
LigandPNGBDBM62233(4-chloro-1-hydroxy-N-(2-methyl-5-nitrophenyl)-2-na...)
Affinity DataIC50: 170nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
LigandPNGBDBM50044276(CHEMBL3321858)
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50556243(CHEMBL4763527)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
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